Polynucleotides vs. PRP: Emerging Treatments for Hair Loss in London
Hair loss, or alopecia, affects millions worldwide, leading to psychological distress and reduced quality of life. Traditional treatments like minoxidil and finasteride have been mainstays, but recent advancements have introduced novel therapies such as polynucleotide (PN) injections and Platelet-Rich Plasma (PRP) therapy. This article delves into these emerging treatments, comparing their mechanisms, efficacy, safety, and cost.
Understanding Polynucleotides
Polynucleotides are natural polymers composed of nucleotide monomers, fundamental to DNA and RNA structures. In medical aesthetics, PNs are utilised for their regenerative properties, promoting tissue repair, reducing inflammation, and enhancing angiogenesis—the formation of new blood vessels. These functions are vital in revitalising hair follicles and stimulating hair growth.
A 2025 study investigated the efficacy of PN injections in patients with androgenetic alopecia (AGA). Twenty-eight participants received four PN injections at four-week intervals. Results showed a significant increase in hair diameter and density, with 82.1% of patients reporting improvement and 60.7% of cases exhibiting stabilisation as per dermatologist assessments. Importantly, no serious side effects were observed, highlighting PNs as a promising alternative for those unresponsive to conventional treatments.

Exploring PRP Therapy
PRP therapy involves extracting a patient's blood, processing it to concentrate platelets, and injecting the platelet-rich plasma into the scalp. Platelets contain growth factors that aid in tissue repair and regeneration, potentially stimulating hair follicles and promoting growth.
Research indicates that PRP can be effective in treating hair loss. A 2020 review of 13 studies found that PRP may help increase hair thickness and density. Another study noted that PRP could trigger hair growth by increasing blood supply to hair follicles.
Comparative Analysis: Efficacy and Safety
Both PN and PRP therapies aim to harness the body's natural healing mechanisms to combat hair loss. The 2025 study on PNs demonstrated significant improvements in hair parameters without serious adverse effects. Similarly, PRP therapy has shown promise in increasing hair density and thickness, with minimal side effects such as scalp tenderness or mild swelling.
However, PRP's efficacy can vary based on individual factors like platelet concentration and overall health. Some studies suggest that higher platelet concentrations in PRP have a more pronounced effect on hair density and follicle diameter.
In contrast, the standardised composition of PNs might offer more consistent results across patients.
Procedure and Treatment Protocols
PN therapy typically involves a series of injections administered at regular intervals. The 2025 study employed four sessions spaced four weeks apart, with measurable improvements observed one month post-treatment.
PRP therapy also requires multiple sessions. A 2019 study compared PRP injections to minoxidil over six months, finding PRP performed better for hair loss. However, individual platelet levels can affect PRP's effectiveness, and maintenance treatments may be necessary.
Cost Considerations
The cost of both treatments varies based on geographic location, provider expertise, and session frequency. In the UK, PRP therapy costs between £200 and £600 per session, with most clinics charging around £300. Polynucleotide treatments are relatively new in the UK market, with limited pricing information available. The Skinoza Clinic offers polynucleotide hair treatments at £240 per session or a package of three sessions for £600. Prospective patients should consult with qualified practitioners to obtain accurate cost estimates and assess the financial feasibility of these therapies.
Conclusion
Polynucleotide and PRP therapies represent promising advancements in the treatment of hair loss, offering alternatives to traditional methods. PN therapy has shown significant improvements in hair diameter and density with a favourable safety profile. PRP therapy has also demonstrated efficacy in promoting hair growth, though individual responses may vary based on platelet concentrations and overall health.
Individuals considering these treatments should consult with qualified healthcare professionals to determine the most suitable option based on their specific condition, medical history, and treatment goals. As research progresses, these therapies may become more refined, accessible, and tailored to individual needs, offering hope to those seeking effective solutions for hair loss.
Recent Developments in Hair Loss Treatments
Read more about polynucleotide Injections London, Side Effects and How to Manage Them here
Check with Skinoza team to see how well you are handling the polynucleotide treatment so you understand what can be done with it. This is all about helping you stay safe and at less of a risk of serious problems when using these.
Ask your trusted Skinoza clinic today for the procedure that suits you! Find Polynucleotide Treatment Near You:
1. Skinoza Orpington, Bromley near Chislehurst, Bickley, Beckenham, West Wickham, Sidcup and Swanley
2. Skinoza Greenwich near Canary Warf, Deptford, Surrey Quays and Kidbrooke Village
3. Skinoza Blackhorse Road, Walthamstow near Tottenham Hale and Seven Sisters
We are experts in polynucleotide treatment for hair loss in London
Please feel free to get in touch for a free consultation and start your journey towards enhanced beauty.
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